Not shortly after Roger Maris record was broken, another baseball player, Jason Giambi and various other athletes were either suspected of, or proven to have, taken anabolic steroids. Again, Congress convened a hearing, and just as they did the first time in 1990, they did not determine that steroids were a danger, but rather that the danger was more in protecting professional sports organizations. The updated statute has been updated to proscribe pro-hormones also The definition of an anabolic steroid as defined currently in the United States under (41)(A) is that "anabolic steroid" means any drug or hormonal substance, chemically and pharmacologically related to testosterone (other than estrogens , progestins, corticosteroids, and dehydroepiandrosterone (7).
The HGH benefits are many, and this leads many people to abuse the compound. They believe if they use more, they’ll experience better results, but this is not at all the case. In fact, this is another similarity between HGH and anabolic steroids – both can cause severe side effects when used in high doses or for long periods of time. Per Dr. Alan Rogol, a representative of The Endocrine Society, HGH can weaken the muscles and cause heart disease when abused. He also notes that the bioavailability of oral HGH is too low for it to be effective, so those purchasing so-called HGH pills online are likely throwing their money away. Finally, per the FDA, excessive use can lead to a variety of cancers. This is why the use of exogenous HGH is so heavily regulated.
Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.